All About Estrogen and 40+/55+

MenoMe 40+ and MenoMe 55+ Capsules in bottle


I thought I ‘knew’ about this very female hormone but my knowledge, as it turns out, has been very limited.

Like most of us, I’ve been aware estrogen is the hormone responsible for the development and maintenance of the female characteristics of the body. However, when I began delving into the signs of menopause I discovered that it does a whole lot more than this. So, when its production in our bodies starts to decline, as it does during menopause, we need to be prepared.

Up Close With Three Important Duties of Estrogen

1. Brain

First up is the important role it plays in managing the chemical activities in our brain.

When estrogen levels are high we feel great. When they decline we can begin to experience anxiety, mood swings, depression, disrupted sleep and fatigue.

2. Skin

Estrogen also plays an important role in maintaining healthy skin, including the stimulation of collagen production and the levels of moisture therein. Therefore diminished estrogen levels invite dry, itchy and thinner skin prone to wrinkles as well as skin disorders such as formication (phantom feeling of ants crawling across the skin).

3. Nervous & Immune Systems

Estrogen has a complex effect on the central nervous system as well as the immune system, by preventing inflammation in the joints. Consequently, its decline can lead to conditions such as paresthesia (numbness and tingling in the extremities – hands and feet) and aching joints.


With those kinds of learnings, I – and probably you – have gained a newfound respect for this female hormone. If you’re anything like me, you’ve probably taken it for granted for most of your life. We just kind of do don’t we?

I hope this little piece helps you understand why our 40+ was once called EstroG-100™ too. It’s because it’s formulated to naturally support our bodies when estrogen – the hormone decides to leave home!

Brilliant really.

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This is the time when menstruation is well and truly over, the ovaries have stopped producing high levels of sex hormones and for many ladies, perimenopause symptoms subside.

Estrogen has protective qualities and the diminished levels mean organs such as your brain, heart and bones become more vulnerable. It’s also a key lubricant so your lips may become drier, your joints less supple and your vagina might be drier. In addition, your thyroid, digestion, insulin, cortisol and weight may alter.

At this juncture, a woman might experience an increase in the signs of reduced estrogen but she should have a decrease of perimenopause symptoms. That said, some women will experience symptoms like hot flushes for years or even the rest of their lives.


Peri = ‘near’

Most females begin to experience the symptoms of perimenopause in their mid-forties. Your progesterone levels decline from your mid-30s but it’s generally from around 40 that the rest of your sex hormones begin to follow suit. 

Perimenopause is a different experience for every woman and some women may barely notice it. The first indicators are usually changes to the monthly cycle. This means that for some ladies, this can be accompanied by things like sore breasts, mood swings, weight gain around the belly, and fatigue as time goes on.

For those with symptoms it can be a challenging time physically, mentally and emotionally.

Importantly, perimenopause lasts – on average – four to 10 years. The transition is usually a gradual process and many women enter perimenopause without realising.